Adjective calloused has 1 sense
  1. calloused, thickened - having skin made tough and thick through wear
    Antonyms: tender, untoughened (indirect, via tough)
,Verb callous has 1 sense
  1. callous, cauterize, cauterise - make insensitive or callous; deaden feelings or morals
    --1 is one way to inure, harden, indurate
    Sample sentence:
    Something ----s somebody
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