Adjective lonesome has 2 senses
- lone, lonesome, only, sole, solitary - being the only one; single and isolated from others; "the lone doctor in the entire county"; "a lonesome pine"; "an only child"; "the sole heir"; "the sole example"; "a solitary instance of cowardice"; "a solitary speck in the sky"
Antonym: multiple (indirect, via single)
- lonely, lonesome - marked by dejection from being alone; "felt sad and lonely"; "the loneliest night of the week"; "lonesome when her husband is away"; "spent a lonesome hour in the bar"
Antonym: elated (indirect, via dejected)
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