Verb loosen up has 5 senses
  1. unstuff, loosen up - cause to become unblocked; "The medicine unstuffed my nose in minutes!"
    --1 is one way to free, disengage
    Sample sentences:
    Somebody ----s something
    Something ----s something
  2. relax, loosen up - become less tense, less formal, or less restrained, and assume a friendlier manner; "our new colleague relaxed when he saw that we were a friendly group"
    --2 is one way to act, behave, do
    Sample sentence:
    Somebody ----s
  3. limber up, warm up, loosen up - make one's body limber or suppler by stretching, as if to prepare for strenuous physical activity
    --3 is one way to exercise, work out
    Sample sentence:
    Somebody ----s
  4. relax, loosen up, unbend, unwind, decompress, slow down - become less tense, rest, or take one's ease; "He relaxed in the hot tub"; "Let's all relax after a hard day's work"
    --4 is one way to change state, turn
    Sample sentence:
    Sam and Sue loosen up
  5. relax, unstrain, unlax, loosen up, unwind, make relaxed - cause to feel relaxed; "A hot bath always relaxes me"
    --5 is one way to affect
    Sample sentence:
    The performance is likely to loosen up Sue
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