Adjective pernicious has 2 senses
  1. baneful, deadly, pernicious, pestilent - exceedingly harmful
    Antonyms: innocuous, harmless (indirect, via noxious)
  2. insidious, pernicious, subtle - working or spreading in a hidden and usually injurious way; "glaucoma is an insidious disease"; "a subtle poison"
    Antonym: harmless (indirect, via harmful)
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