Adjective estranged has 1 sense
  1. alienated, estranged - caused to be unloved
    Antonym: loved (indirect, via unloved)
,Verb estrange has 2 senses
  1. estrange - remove from customary environment or associations; "Her busy schedule removed her from her duties as a mother"
    --1 is one way to
    take out, move out, remove
    Derived form: noun estrangement2
    Sample sentences:
    Somebody ----s somebody
    Something ----s somebody
  2. estrange, alienate, alien, disaffect - arouse hostility or indifference in where there had formerly been love, affection, or friendliness
    --2 is one way to change, alter, modify
    Derived form: noun estrangement1
    Sample sentence:
    The performance is likely to estrange Sue
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