- cranky, fractious, irritable, nettlesome, peevish, peckish, pettish, petulant, testy, tetchy, techy - easily irritated or annoyed; "an incorrigibly fractious young man"; "not the least nettlesome of his countrymen"
Antonym: good-natured (indirect, via ill-natured)
- irritable - abnormally sensitive to a stimulus
Antonym: insensitive (indirect, via sensitive)
- excitable, irritable - capable of responding to stimuli
Antonym: insensitive (indirect, via sensitive)