Adjective pestiferous has 4 senses
  1. contaminated, dirty, infected, pestiferous - contaminated with infecting organisms; "dirty wounds"; "obliged to go into infected rooms"- Jane Austen
    Antonym: antiseptic (indirect, via septic)
  2. pestilent, pestilential, pestiferous, plaguey - likely to spread and cause an epidemic disease; "a pestilential malignancy in the air"- Jonathan Swift; "plaguey fevers"
    Antonyms: endemic, endemical (indirect, via epidemic, ecdemic)
    Antonym: ecdemic (indirect, via endemic, epidemic)
  3. corruptive, perversive, pestiferous - tending to corrupt or pervert
    Antonym: good (indirect, via evil)
  4. annoying, bothersome, galling, irritating, nettlesome, pesky, pestering, pestiferous, plaguy, plaguey, teasing, vexatious, vexing - causing irritation or annoyance; "tapping an annoying rhythm on his glass with his fork"; "aircraft noise is particularly bothersome near the airport"; "found it galling to have to ask permission"; "an irritating delay"; "nettlesome paperwork"; "a pesky mosquito"; "swarms of pestering gnats"; "a plaguey newfangled safety catch"; "a teasing and persistent thought annoyed him"; "a vexatious child"; "it is vexing to have to admit you are wrong"
    Antonym: agreeable (indirect, via disagreeable)
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