Verb let loose has 2 senses
  1. utter, emit, let out, let loose - express audibly; utter sounds (not necessarily words); "She let out a big heavy sigh"; "He uttered strange sounds that nobody could understand"
    Sample sentences:
    Somebody ----s something
    Something ----s something
  2. unleash, let loose, loose - turn loose or free from restraint; "let loose mines"; "Loose terrible plagues upon humanity"
    --2 is one way to let go of, let go, release, relinquish
    Sample sentences:
    Somebody ----s something
    Somebody ----s somebody
    Something ----s somebody
    Something ----s something
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